Bruce N. Ames 2007 Publications

511. Jia L, Liu Z, Miller SS, Ames BN, and Liu J. (2007) (R)-alpha-Lipoic acid protects retinal pigment epithelial cells from damage by acrolein, a toxin in cigarette smoke: Relevance to macular degeneration. Invest. Ophthalmol. Vis. Sci., 48: 339-48.

512. Atamna H, Newberry J, Erlitzki R, Schultz CS, and Ames BN (2007) Biotin Deficiency Inhibits Heme Synthesis and Impairs Mitochondria in Human Lung Fibroblasts. J of Nutr, 137:25-30.

513. Offer T, Ames BN, Bailey SW, Sabens EA, Nozawa M, and Ayling JE (2007) 5-Methyltetrahydrofolate inhibits photosensitization reactions and strand breaks in DNA. FASEB J. 2007 21: 2101-7.

514. McCann, J., Ames, BN. (2007) An Overview of Evidence For a Causal Relationship Between Iron Deficiency During Development and Deficits in Cognition or Behavior, Am J Clin Nutr. 85:931-45.

515. Wallock-Montelius LM, Villanueva JA, Chapin RC, Conley A, Nguyen HP, Ames BN, and Halsted CH. (2007) Chronic Ethanol Perturbs Testicular Folate Metabolism and Dietary Folate Deficiency Reduces Sex Hormone Levels in the Yucatan Micropig Biology of Reproduction.76: 455-65.

515a. McMackin CJ, Widlansky ME, Hamburg NM, Huang AL, Weller S, Holbrook M, Gokce N, Hagen TM, Keaney JF Jr, Vita JA. (2007)Effect of combined treatment with alpha-Lipoic acid and acetyl-L-carnitine on vascular function and blood pressure in patients with coronary artery disease.J Clin Hypertens (Greenwich) 9(4):249-55.

515b. Schwarzera C, Illek B, Suh JH, Remingtonc SJ, Fischer H, Machena TE (2007) Organelle Redox of CF and CFTR-Corrected Airway Epithelia. Free Radical Biology and Medicine. Available Online 29 April 2007 doi:10.1016/j.freeradbiomed.2007.04.015

516. McCann JC and Ames BN (2007) DHA and Cognitive Development. Pediatric Basics 117: 16-22.

517. Ames BN, McCann JC, Stampfer MJ, Willett WC (2007) Letter to the Editor: Evidence-based decision making on micronutrients and chronic disease: long-term randomized controlled trails are not enough. Amer J Clin Nutr 86:522-3.

518. Wagner JG, Jiang Q, Harkema JR, Illek B, Patel DD, Ames BN, Peden DB (2007) Ozone Enhancement of Lower Airway Allergic Inflammation is Prevented By -Tocopherol. FRBM 43:1176-88.

519. Milgram NW, Araujo JA, Hagen TM, Treadwell BV, Ames BN (2007) Acetyl-L-carnitine and alpha-lipoic acid supplementation of aged beagle dogs improves learning in two landmark discrimination tests. FASEB J. 21:3756-62.

519a. Atamna H, Frey WH (2007) Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimers disease Mitochondrion 7:297-310.

519b. Killilea AN, Downing KH, Killilea DW (2007) Zinc deficiency reduces paclitaxel efficacy in LNCaP prostate cancer cells. Cancer Letters, 258:70-9.

520. McCann JC, Ames BN. Lessons from DHA trials on cognition/behavior in humans and animals(in Dutch). In: Special Fatty Acids. Scientific publication on infant nutrition (ed. FAJMuskiet). Elsevier Health Care, The Netherlands , October 2007, pp15-17.

521. Voloboueva LA, Killilea DW, Atamna H, Ames BN (2007) N-t-butyl hydroxylamine, a mitochondrial antioxidant, protects from excess iron in a human retinal pigment epithelial cell model of macular degeneration. FASEB J., 21:4077-4086.

522. Ames, BN and McCann, JC (2007) Triage: why micronutrient inadequacy appears to lead to DNA damage, premature aging, and other long-term toxic effects. Toxicological Sciences. NOTE : REJECTED - Tox Sci gave us the option to write an editorial and there were so many other things going on we decided not to. J

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

Information on Juvenon

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