Bruce N. Ames 1999 Publications

409. Lykkesfeldt, J. and Ames, B.N. (1999) Ascorbic Acid Recycling in Rat Hepatocytes as a Measurement of Antioxidant Capacity: Decline with Age. In: Methods in Enzymology, L. Packer, ed. (Academic Press, San Diego, Ca), vol. 299, pp. 83-87. check for PDF

410. Ames, B.N. and Gold, L.S. (1999) The Prevention of Cancer. In: Functional Foods for Disease Prevention I: Fruits, Vegetables, and Teas, T. Shibamoto, J. Terao, and T. Osawa, eds. (American Chemical Society, Washington, D.C.) pp. 2-15. check for PDF

411. Yeo, H. C., Liu, J. K., Helbock, H. J. and Ames, B. N. (1999) Assay of Malondialdehyde and Other Alkanals in Biological Fluids by Gas Chromatography - Mass Spectrometry. In: Nitric Oxide, Part C: Biological and Antioxidant Activities - Methods in Enzymology, L. Packer, ed. (Academic Press, San Diego, CA), vol. 300, pp. 70-78. check for PDF

412. Helbock, H. J., Beckman, K B., and Ames, B. N. (1999) 8-Hydroxydeoxyguanosine and 8-Hydroxyguanine as Biomarkers of Oxidative DNA Damage. In Oxidants and Antioxidants -Methods in Enzymology, L. Packer, ed. (Academic Press, San Diego, CA), vol. 300, pp. 156-166. check for PDF

413. Christen, S., Hagen, T.M., Shigenaga, M.K., and Ames, B.N. (1999) Chronic Infection and Inflammation Lead to Mutation and Cancer. In: Microbes and Malignancy: Infection as a Cause of Cancer , J. Parsonnet and S. Horning, eds. (Oxford University Press, New York), pp. 35- 88. check for PDF

414. Walter, P. B., Beckman, K. B. and Ames, B. N. (1999) The Role of Iron and Mitochondria in Aging. In: Understanding the Process of Aging; Mitochondria, Oxidants, and Aging, E. Cadenas and L. Packer, eds. (Marcel Dekker, Inc., New York), pp. 203-227. check for PDF

415. Beckman, K. B. and Ames, B. N. (1999) Endogenous Oxidative Damage of mtDNA. Mutat. Res. 424, 51-58. check for PDF

416. Hagen, T. M., Ingersoll, R. T., Liu, J., Lykkesfeldt, J., Wehr, C. M., Vinarsky, V., Bartholomew, J. C. and Ames, B. N. (1999) (R)-α-Lipoic Acid-Supplemented Old Rats Have Improved Mitochondrial Function, Decreased Oxidative Damage, and Increased Metabolic Rate. FASEB J 13, 411-418. check for PDF

417. Ames, B. N. and Gold, L. S. (1999) [Foreword]. In: Toxicology, H. Marquardt, S. Schäfer, R. O. McClellan, F. Welsch, eds. (Academic Press, San Diego, CA), pp. 1-7. check for PDF

418. Ames, B. N. (1999) Micronutrient Deficiencies: A Major Cause of DNA Damage. In: Cancer Prevention: Novel Nutrient and Pharmaceutical Developments, H. L. Bradlow and M. Osborne, eds. (New York Academy of Sciences, NY), vol. 889, pp. 87-106. check for PDF

419. Ames, B. N. (1999) Cancer Prevention and Diet: Help from SNPs [Commentary]. Proc. Natl. Acad. Sci. U.S.A. 96, 12216-12218. check for PDF

420. Ames, B. N. (1999) Micronutrient Deficiencies Cause DNA Damage and Cancer. Food Sci. Agric. Chem. J. 1, 1-15. check for PDF

421. Ames, B. N., and Gold. L. S. (1999) Neuf Idées Reçues Passées au Crible de la Science. La Recherche, 47-53. check for PDF

422. Ames, B. N. (1999) [Book Review]. Reason: December 1999;p.21. check for PDF

423. Ames, B. N., and Gold, L. S. (1999) Pollution, Pesticides and Cancer Misconceptions. In: Fearing Food: Risk, Health and Environment, J. Morris and R. Bate, eds. (Butterworth-Heinemann, Oxford), pp. 19-37. check for PDF

423a. Liu, J. and Mori, A. (1999) Stress, Aging, and Brain Oxidative Damage. Neurochem. Res. 24, 1479-1497. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

Information on Juvenon

Please request all Juvenon related inquiries to Juvenon.