Bruce N. Ames 2004 Publications

482. Courtemanche, C., Huang, A.C., Elson-Schwab, I., Kerry, N., Ng, B.Y. and Ames, B.N. (2004) Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison. FASEB J 18:209-11. doi:10.1096/fj.03-0382fje check for PDF

483. Ames, B.N. (2004) A Role for Supplements in Optimizing Health: The Metabolic Tune-Up. Arch Biochem Biophys., 423: 227-234. check for PDF

484. Ames, B.N. (2004) Mitochondrial Decay, A Major Cause of Aging, Can Be Delayed. J. Alz. Dis., 6: 117-21. check for PDF

485. Mashiyama, S., Courtemanche, C., Elson-Schwab, I., Crott, J., Lan Lee, B., NamOng, C., Fenech, M. and Ames, B.N. (2004) Uracil in DNA, determined by an improved assay, is increased when deoxynucleosides are added to folate-deficient cultured human lymphocytes. Analytical Biochemistry. 330: 58-69. check for PDF

486. Killilea, D.W., Wong, S.L., Cahaya, H.S., Atamna, H., and Ames, B.N. (2004) Iron Accumulation during Cellular Senescence. Ann NY Acad Sci 1019: 365-367. check for PDF

487. Ames, B.N. (2004) Delaying the Mitochondrial Decay of Aging. Ann NY Acad Sci 1019: 406-411. check for PDF

488. Ames, B.N. (2004) Supplements and Tuning Up Metabolism, J Nutr. 134:3164S-8S. check for PDF

489. Liu, J., Head, E., Kuratsune, H., Cotman, C.W. and Ames, B.N. (2004) Comparison of the effects of L-carnitine and acetyl-L-carnitine on carnitine levels, ambulatory activity, and oxidative stress biomarkers in the brain of old rats. Ann NY Acad Sci. 1033: 117-131. check for PDF

490. Ames, B.N. & Liu, J. (2004) Delaying the Mitochondrial Decay of Aging with Acetyl Carnitine. Ann NY Acad Sci. 1033: 108-116. check for PDF

491. Courtemanche, C., Elson-Schwab, I., Mashiyama S.T., Kerry, N. and Ames B.N. (2004) Folate deficiency inhibits the proliferation of primary human CD8+ T lymphocytes in vitro. J Immunol. 173:3186-3192. check for PDF

492. Jiang, Q., Wong, J. and Ames, B.N. (2004) γ-Tocopherol induces apoptosis in androgen-responsive LNCaP prostate cancer cells via caspase dependent and independent mechanism. Ann NY Acad Sci, 1031:399-400. check for PDF

493. Jiang, Q., Wong, J., Fyrst, H., Saba, J.D. and Ames, B.N. (2004) γ-Tocopherol, or Combinations of Vitamin E Forms, Induce Cell Death In Human Prostate Cancer Cells By Interrupting Sphingolipid Synthesis. PNAS, 101: 17825-17830. check for PDF

493a. Atamna, H. (2004) Review article: Heme, iron, and the mitochondrial decay of ageing. Ageing Res Rev. 3: 303-318. check for PDF

493b. Atamna, H. and Frey, W.H. (2004) A Role for Heme in Alzheimer’s Disease: Heme Binds Amyloid-β and has Altered Metabolism PNAS 101: 11153-58. check for PDF

493c. Suh, J., Wang, H., Liu, R.M., Liu, J. and Hagen, T.M. (2004) (R)-α-Lipoic acid reverses the age-related loss in GSH redox status in post-mitotic tissues: evidence for increased cysteine requirement for GSH synthesis. Arch Biochem Biophys. 423:126-35. check for PDF

493d. Zhang, X., Leung S-M, Morris, C.R., Shigenaga, M.K. (2004) Evaluation of a Novel, Integrated Approach Using Fictionalized Magnetic Beads, Bench-Top MALDI-TOF-MS with Prestructured Sample Supports, and Pattern Recognition Software for Profiling Potential Biomarkers in Human Plasma. J Biomol Tech 15:167-75. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

Information on Juvenon

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