Bruce N. Ames 1990 Publications

246 Lemke, M., Frei, B., Ames, B. N. and Faden, A. I. (1990) Decreases in Tissue Levels of Ubiquinol-9 and -10, Ascorbate and alpha-tocopherol Following Spinal Cord Impact Trauma in Rats. Neuroscience Letters 108, 201-206. check for PDF

247 Ames, B. N. (1990) Natural Carcinogens: They're Found in Many Foods. In: Health & Environment Digest, B. Murdock, ed., pp. 4. check for PDF

248 Gold, L. S., Slone, T. H., Backman, G. M., Eisenberg, S., Da Costa M., Wong, M., Manley, N. B., Rohrbach, L. and Ames, B. N. (1990) Third Chronological Supplement to the Carcinogenic Potency Database: Standardized Results of Animal Bioassays Published Through December 1986 and by the National Toxicology Program Through June 1987. Environ. Health Perspect. 84, 215-285. check for PDF

249 Storz, G., Tartaglia, L. A. and Ames, B. N. (1990) Transcriptional Regulator of Oxidative Stress-Inducible Genes: Direct Activation by Oxidation. Science 248, 189-194. check for PDF

250 Cross, C. E., Forte, T., Stocker, R., Louie, S., Yamamoto, Y., Ames, B. N. and Frei, B. (1990) Oxidative Stress and Abnormal Cholesterol Metabolism in Patients with Adult Respiratory Distress Syndrome. J. Lab. Clin. Med. 115, 396-404. check for PDF

251 Stocker, R., McDonagh, A. F., Glazer, A. N. and Ames, B. N. (1990) Antioxidant Activities of Bile Pigments: Biliverdin and Bilirubin. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, J. N. Abelson and M. I. Simon, eds. (Academic Press, New York, NY), Vol. 186, 301-309. check for PDF

252 Yamamoto, Y., Frei, B. and Ames, B. N. (1990) Assay of Lipid Hydroperoxides Using HPLC with a Isoluminal Chemiluminescence Detection. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, Part B: Oxygen Radicals and Antioxidants, L. Packer and A. Glazer, eds. (Academic Press, New York, NY), Vol. 186, 371-380. check for PDF

253 Shigenaga, M. K., Park, J.-W., Cundy, K. C., Gimeno, C. J. and Ames, B. N. (1990) In vivo Oxidative DNA Damage: Measurement of 8-Hydroxy-2'-deoxyguanosine in DNA and Urine by High-Performance Liquid Chromatography with Electrochemical Detection. In: Methods in Enzymology: Oxygen Radicals in Biological Systems, Part B: Oxygen Radicals and Antioxidants, L. Packer and A. Glazer, eds. (Academic Press, New York, NY), Vol. 186, 521-530. check for PDF

254 Fraga, C. G., Shigenaga, M. K., Park, J.-W., Degan, P. and Ames, B. N. (1990) Oxidative Damage to DNA During Aging: 8-Hydroxy-2'-deoxyguanosine in Rat Organ DNA and Urine. Proc. Natl. Acad. Sci. USA 87, 4533-4537. check for PDF

255 Ames, B. N. and Gold, L. S. (1990) Dietary Carcinogens, Environmental Pollution, and Cancer: Some Misconceptions. Med. Oncol. & Tumor Pharmacother. 7, 69-85. check for PDF

256 Frei, B., Kim, M. C. and Ames, B. N. (1990) Ubiquinol-10 is an Effective Lipid-Soluble Antioxidant at Physiological Concentrations. Proc. Natl. Acad. Sci. USA 87, 4879-4883. check for PDF

257 Ames, B. N. and Gold. L. S. (1990) Too Many Rodent Carcinogens: Mitogenesis Increases Mutagenesis. Science 249, 970-971. check for PDF

258 Tartaglia, L. A., Storz, G., Brodsky, M. H., Lai, A. and Ames, B. N. (1990) Alkyl Hydroperoxide Reductase from S. typhimurium Sequence and Homology to Thioredoxin Reductase and Other Flavoprotein Disulfide Oxidoreductases. J. Biol. Chem. 265, 10535-10540. check for PDF

259 Ames, B. N. and Gold, L. S. (1990) Chemical Carcinogenesis: Too Many Rodent Carcinogens. Proc. Natl. Acad. Sci. USA 87, 7772-7776. check for PDF

260 Ames, B. N., Profet, M. and Gold, L. S. (1990) Dietary Pesticides (99.99% All Natural). Proc. Natl. Acad. Sci. USA 87, 7777-7781. check for PDF

261 Ames, B. N., Profet, M. and Gold. L. S. (1990) Nature's Chemicals and Synthetic Chemicals: Comparative Toxicology. Proc. Natl. Acad. Sci. USA 87, 7782-7786. check for PDF

261a MacGregor, J. T. (1990) Dietary Factors Affecting Spontaneous Chromosomal Damage in Man. In: Mutagens and Carcinogens in the Diet (Wiley-Liss, Inc., NY), pp. 139-153. check for PDF

262 Storz, G., Tartaglia, L. A., Farr, S. B. and Ames, B. N. (1990) Bacterial Defenses Against Oxidative Stress. Trends Genet. 6, 363-368. check for PDF

263 Storz, G., Tartaglia, L. A. and Ames, B. N. (1990) The OxyR Regulon. Antonie van Leeuwenhoek 58, 157-161. check for PDF

264 Frei, B., Stocker, R., England, L. and Ames, B. N. (1990) Ascorbate: The Most Effective Antioxidant in Human Blood Plasma. Adv. Exp. Med. Biol. 264, 155-164. check for PDF

265 Ames, B. N. and Gold, L. S. (1990) Misconceptions on Pollution and the Causes of Cancer. Angew. Chem. 29, 1197-1208. check for PDF

266 MacGregor, J. T., Schlegel, R., Wehr, C. M., Alperin, P. and Ames, B. N. (1990) Cytogenetic Damage Induced by Folate Deficiency in Mice is Enhanced by Caffeine. Proc. Natl. Acad. Sci. USA 87, 9962-9965. check for PDF

267 Ames, B. N. and Gold, L. S. (1990) Carcinogenesis Debate (Letter). Science 250, 1498-1499. check for PDF

268 Ames, B. N. and Gold, L. S. (1990) Carcinogens and Human Health: Part 1 (Letter). Science 250, 1645-1646. check for PDF

269 Ames, B. N. and Gold, L. S. (1990) Carcinogens and Human Health: Part 2 (Letter). Science 251, 12-13. check for PDF

270 Ames, B. N. (1990) Misconceptions About Pollution and Cancer. National Review, December 3. check for PDF

271 Gold, L. S., Bernstein, L. and Ames, B. N. (1990) The Importance of Ranking Possible Carcinogenic Hazards Using HERP. Risk Anal. 10, 625-628. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

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