Bruce N. Ames 2005 Publications

494. Offer, T., Ho, E., Traber, M.G., Bruno, R.S., Kuypers, F.A., and Ames B.N. (2005) A Simple Assay for Frequency of Chromosome Breaks and Loss (Micronuclei) by Flow Cytometry of Human Reticulocytes. FASEB J., 19:485-7 doi: 10.1096/fj.04-2729fje. check for PDF

495. Liu, J and Ames, BN (2005) Review: Reducing mitochondrial decay with mitochondrial nutrients to delay and treat cognitive dysfunction, Nutritional Neuroscience, 8:67-89. check for PDF

496. Kadiiska, M.B., Gladen, B.C., Baird, D.D., Germolec, D., Graham, L.B., Parker, C.E., Nyska, A., Wachsman, J.T., Ames, B.N, Basu S., Brot, N., FitzGerald, G.A., Floyd, R.A., George, M., Heinecke, J.W., Hatch, G.E., Hensley, K., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sohal, R.S., Sun, J., Tice, R.R., Van Thiel, D.H., Wellner, D., Walter, P.B., Tomer, K.B., Mason, R.P., Barrett, J.C. (2005) Biomarkers of Oxidative Stress Study II: Are oxidation products of lipids, proteins, and DNA markers of CC14 poisoning? Free Radic Biol Med. 38:698-710. check for PDF

497. Kadiiska, M.B., Gladen, B.C., Baird, D.D., Graham, L.B., Parker, C.E., Ames, B.N, Basu S., FitzGerald, G.A., Lawson, J.A., Marnett, L.J., Morrow, J.D., Murray, D.M., Plastaras, J., Roberts, L.J., Rokach, J., Shigenaga, M.K., Sun, J., Walter, P.B., Tomer, K.B., Barrett, J.C. Mason, R.P. (2005) Biomarkers of Oxidative Stress Study III: Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CC14 poisoning? Free Radic Biol Med. 38:711-8. check for PDF

497a. Walter, P.B., Fung, E.B., Killilea, D.W., Jiang, Q., Hudes, M., Porter, J., Evans, P., Vichinsky, E., and Harmatz, P. (2005) Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease. British Journal of Haematology 135:254-63.

498. McCann, J.C. and Ames, B.N. (2005) Is docosahexaenoic acid (DHA), an n-3 long chain polyunsaturated fatty acid, required for normal brain function? An overview of evidence from cognitive and behavioral tests in humans and animals: a review. Am J Clin Nutr. 82: 281-95. check for PDF

499. Voloboueva, L.A., Liu, J., Suh, J.H., Ames, B.N. and Miller S.S. (2005) (R)-α-Lipoic Acid Protects Retinal Pigment Epithelial Cells From Oxidative Damage IOVS, 46:4302-4310. check for PDF

500. Ames, B.N. (2005) Increasing Longevity by Tuning-up Metabolism, EMBO Reports, 6:S20-4. check for PDF

501. Liu, J. and Ames, B.N. (2005) Mitochondrial nutrients: Reducing mitochondrial decay to delay or treat cognitive dysfunction, Alzheimer's disease, and Parkinson's disease, In: Neurodegenerative Disorders, Aging and Antioxidants. Editors Y. Luo and L. Packer. p 59-105. check for PDF

502. Ames BN. (2005) DNA and Mitochondrial Damage from Inadequate Micronutrient Intake In: The Textbook of Functional Medicine, eds. D.S. Jones and S. Quinn, The Institute of Functional Medicine. Washington 397-412. check for PDF

503. Kaput J, Ordovs, JM, Ferguson L, van Ommen B, Rodriguez RL, Allen L, Ames BN, et al. (2005) Horizons in Nutritional Science: The Case for Strategic International Alliances to Harness Nutritional Genomics for Public and Personal Health. British J Nutrition, 94:623-32. check for PDF

504. Ames, B.N., Atamna, H. and Killilea, D. (2005) Review: Mineral and Vitamin Deficiencies Can Accelerate the Mitochondrial Decay of Aging. Molecular Aspects of Medicine, 26: 363-78. check for PDF

505. Ames, B. (2005) The Metabolic Tune-up for Disease Prevention, FasterCures SmartBrief – Milken Institute, Milken Institute http://www.fastercures.org/sec/essay_ames check for PDF

506. Offer, T., Bhagat, A., Lal, A., Atamna, W., Singer, S.T., Vichinsky, E.P., Kuypers, F.A. & Ames, B.N. (2005) Measuring Chromosome Breaks in Patients with Thalassemia. Ann. N.Y. Acad. Sci. 1054: 439-44. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Dr. Ames current lecture abstract presented at CHORI, January 11, 2012 - Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Go to media page

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