Bruce N. Ames 1998 Publications

390. Ames, B. N. and Gold, L. S. (1998) Misconceptions About Environmental Pollution, Pesticides and the Causes of Cancer. National Center for Policy Analysis, Dallas, Texas, NCPA Policy Report No. 214, March 1998. check for PDF

391. Yeo, H. C., Helbock, H. J. and Ames, B. N. (1998) Toxic Carbonyl Compound. In: Chromatographic Analysis of Environmental and Food Toxicants, T. Shibamoto, ed. (Marcel Dekker, NY), pp. 289-322. check for PDF

392. Ames, B. N., Gold, L. S. and Willett, W. C. (1998) Neoplasie: Cause e Prevenzione. In: Enciclopedia Del Novecento, (Istituto dellÕEnciclopedia Italiana), pp. 341-350. [reprint of #346] check for PDF

393. Liu, J., Yokoi, I., Doniger, S. J., Kabuto, H., Mori, A. and Ames, B. N. (1998) Adrenalectomy Causes Oxidative Damage and Monoamine Increase in the Brain of Rats and Enhance Immobilization Stress-Induced Oxidative Damage and Neurotransmitter Changes, Int. J. Stress. Manag. 5, 39-55. check for PDF

394. Beckman, K. B. and Ames, B. N. (1998) The Free Radical Theory of Aging Matures. Physiol. Rev. 78, 547-581. check for PDF

395. Chen, Q. M., Bartholomew, J. C., Campisi, J., Acosta, M., Reagan, J. D., and Ames, B. N. (1998) Molecular Analysis of H2O2-induced Senescent-like Growth Arrest in Normal Human Fibroblasts: p53 and Rb control G1 Arrest but Not Cell Replication. Biochem. J. 332, 43-50. check for PDF

396. Ames, B. N. and Gold, L. S. (1998) The Prevention of Cancer. Drug Metab. Rev. 30, 203-225. check for PDF

397. Gold, L. S., Slone, T. H. and Ames, B. N. (1998) What do Animal Cancer Tests Tell Us About Human Cancer Risk?: Overview of Analyses of the Carcinogenic Potency Database. Drug Metab. Rev. 30, 359-404. check for PDF

398. Yowe, D. L. and Ames, B. N. (1998) Quantitation of Age-related Mitochondrial DNA Deletions in Rat Tissues Shows their Pattern of Accumulation Differs from that of Humans. Gene 209, 23-30. check for PDF

399. Ames, B. N. (1998) Nutrition and the Degenerative Diseases of Aging. In: From Nutritional Science to Nutrition Practice for Better Global Health. Proceedings of the 16th International Congress of Nutrition 1997 Jul 27-Aug 1 ; Montreal, Canada (Canadian Federation of Biological Societies, Ontario, Canada, pp. 225-227. check for PDF

400. Ames, B. N. (1998) Micronutrients Prevent Cancer and Delay Aging. Toxicol. Lett. 102, 5-18. check for PDF

401. Helbock, H. J., Beckman, K. B., Walter, P., Shigenaga, M. K., Woodall, A. A., Yeo, H. C. and Ames, B. N. (1998) DNA Oxidation Matters: The HPLC-electrochemical Detection Assay of 8-oxo-deoxyguanosine and 8-oxo-guanine. Proc. Natl. Acad. Sci. USA 95, 288-293. check for PDF

402. Ames, B. N. and Gold, L. S. (1998) The Rodent High-Dose Cancer Test is Limited at Best: When Cell Division is Ignored, then Risk Assessment will be Flawed. Comments Toxicol. 6, 271-276. check for PDF

403. Beckman, K. B. and Ames, B. N. (1998) Mitochondrial Aging: Open Questions. In: Towards Prolongation of the Healthy Life Span: Practical Approaches to Intervention, D. Harman, R. Holliday, M. Meydani, eds. (New York Acad Sci, New York, NY), vol. 854, pp. 118-127. check for PDF

404. Beckman, K.B. and Ames, B.N. (1998) Oxidative DNA Damage: Assessing its Role in Cancer and Aging. In: DNA & Free Radicals: Techniques, Mechanisms and Applications, O.I. Aruoma and B. Halliwell, eds. (OICA International, St. Lucia, West Indies), pp. 119-129. check for PDF

405. Lykkesfeldt, J., Hagen, T. M., Vinarsky, V., and Ames, B. N. (1998) Age-associated Decline in Ascorbic Acid Concentration, Recycling and Biosynthesis in Rat Hepatocytes Ñ Reversal with (R)-alpha-Lipoic Acid Supplementation. FASEB J.12, 1183-1189. check for PDF

406. Hagen, T. M., Wehr, C. M., and Ames, B. N. (1998) Mitochondrial Decay in Aging: Reversal through Dietary Supplementation of Acetyl-L-Carnitine and N-tert-Butyl-α-Phenyl-Nitrone. In: Towards Prolongation of the Healthy Life Span: Practical Approaches to Intervention, D. Harman, R. Holliday, M. Meydani, eds. (New York Acad Sci, New York, NY), vol. 854, pp. 214-223. check for PDF

407. Ames, B. N. and Gold, L. S. (1998) The Causes and Prevention of Cancer: The Role of Environment. Biotherapy 11, 205-220. check for PDF

408. Hagen, T. M., Ingersoll, R. T., Wehr, C. M., Lykkesfeldt, J., Vinarsky, V., Bartholomew, J. C., Song, M.H. and Ames, B. N. (1998) Acetyl-L-Carnitine Fed to Old Rats Partially Restores Mitochondrial Function and Ambulatory Activity. Proc. Natl. Acad. Sci. USA 95, 9562-9566. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

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