Bruce N. Ames 2000 Publications

424. Beckman, K.B. and Ames B.N. (2000) Oxidants and aging. In: Handbook of Oxidants and Antioxidants in Exercise, C.K. Sen, L. Packer, O.O.P. Hanninen, eds. (Elsevier, Amsterdam), pp. 755-796. check for PDF

425. Ames, B. N. and Gold, L. S. (2000) Paracelsus to Parascience: The Environmental Cancer Distraction. Mutat. Res. 447, 3-13. check for PDF

426. Atamna, H., Cheung, I., and Ames, B. N. (2000) A Method for Detecting Abasic (AP) Sites in Living Cells: Age-dependent Changes in Base Excision Repair. Proc. Natl. Acad. Sci. U.S.A. 97, 686-691. check for PDF

427. Knutson, M. D, Walter, P. B., Ames, B. N., and Viteri, F. E. (2000) Both Iron Deficiency and Daily Iron Supplements Increase Lipid Peroxidation in Rats. J. Nutr. 130, 621-628. check for PDF

428. Lykkesfeldt, J., Christen, S., Wallock, L. M., Chang, H. H., Jacob, R. A. and Ames, B. N. (2000) Ascorbate is Depleted by Smoking and Repleted by Moderate Supplementation: A Study in Male Smokers and Non-smokers with Matched Dietary Antioxidant Intakes. AJCN 71, 530-536. check for PDF

429. Atamna, H., Paler-Martinez, A., and Ames, B. N. (2000) N-t-butyl Hydroxlamine, a Hydrolysis Product of α-phenyl-N-t-butyl Nitrone, is More Potent in Delaying Senescence in Human Lung Fibroblasts. J. Biol. Chem. 275, 6741-6748. check for PDF

430. Ames, B. N. and Gold, L. S. (2000) Misconceptions about Environmental Pollution In: The Standard Handbook of Environmental Science Health and Technology, J. Lehr, ed. (McGraw-Hill, Inc.), chap. 21, p. 21.1 - 21.16. check for PDF

431. Higdon, J. V., Liu, J., Du, S.H., Morrow, J. D., Ames, B. N., and Wander, R. C. (2000) Supplementation of Postmenopausal Women with Fish Oil Rich in Eicosapentaenoic Acid and Docosahexaenoic Acid is Not Associated with Greater In Vivo Lipid Peroxidation Compared with Oils Rich in Oleate and Linoleate as Assessed By Plasma Malondialdehyde and F2-Isoprostanes. Am. J. Clin. Nutr. 72, 714-22. check for PDF

432. Liu, J., Yeo, H. C., Overvik-Douki, E., Hagen, T., Doniger, S. J., Chu, D. W., Brooks, G. A., and Ames, B. N. (2000) Chronically and Acutely Exercised Rats: Biomarkers of Oxidative Stress and Endogenous Antioxidants. J. Appl. Physiol. 89, 21-28. check for PDF

433. Hagen, T. M., Vinarsky, V., Wehr, C. M., and Ames, B. N. (2000) (R)-α-Lipoic Acid Reverses the Age-Associated Increase in Susceptibility of Hepatocytes to tert-Butylhydroperoxide both In Vitro and In Vivo. Antiox. & Redox Signal. 2, 473-483. check for PDF

434. Soultanakis, R.P., Melamede, R.J., Bespalov, I.A., Wallace, S.S., Beckman, K.B., Ames, B.N., Taatjies, D.J., and Janssen-Heininger, Y.M.W. (2000) Fluorescence Detection of 8-oxoguanine in Nuclear and Mitochondrial DNA of Cultured Cells Using a Recombinant Fab and Confocal Scanning Laser Microscopy. Free Radic. Biol. Med. 28, 987-998. check for PDF

435. Jiang, Q., Elson-Schwab, I., Courtemanche, C. and Ames, B.N. (2000) γ-Tocopherol and its Major Metabolite, in Contrast to α-Tocopherol, Inhibit Cyclooxgenase Activity in Macrophages and Epithelial Cells. Proc. Natl. Acad. Sci. U.S.A. 97, 11494-11499. check for PDF

436. Beckman, K.B., Saljoughi, S., Mashiyama, S.T., and Ames, B.N. (2000) A Simpler, More Robust Method for the Analysis of 8-Oxoguanine in DNA. Free Radic. Biol. Med. 29, 357-367. check for PDF

437. Gogvadze, V., Klein, S.D., Shigenaga, M., Ames, B.N., and Richter, C. (2000) Effect of Ebselen on Ca2+ Transport in Mitochondria. Redox Report 5, 359-363. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Dr. Ames current lecture abstract presented at CHORI, January 11, 2012 - Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Go to media page

Information on Juvenon

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