Bruce N. Ames 1991 Publications

272 Ames, B. N. and Gold, L. S. (1991) Carcinogens and Human Health: Part 3 (Letter). Science 251, 606-608. check for PDF

273 Ames, B. N., Profet, M. and Gold. L. S. (1991) Dietary Carcinogens and Mutagens from Plants. In: Mutagens in Food: Detection and Prevention, H. Hayatsu, ed. (CRC Press, Inc., Boca Raton, FL), pp. 29-50. check for PDF

274 Ames, B. N. (1991) Endogenous DNA Damage as Related to Nutrition and Aging. In: The Potential for Nutritional Modulation of Aging Processes, D. K. Ingram, G. T. Baker III and N. W. Shock, eds. (Food and Nutrition Press, Inc., Turnbull, CT), pp. 251-261. check for PDF

275 Ames, B. N. and Gold, L. S. (1991) Cancer Prevention Strategies Greatly Exaggerate Risks. Chem. Engr. News 69, 28-32. check for PDF

276 Shigenaga, M. K. and Ames, B. N. (1991) Assays for 8-Hydroxy-2'-deoxyguanosine: A Biomarker of in vivo Oxidative DNA Damage. Free Rad. Biol. Med. 10, 211-216. check for PDF

277 Degan, P., Shigenaga, M. K., Park, E.-M., Alperin, P. and Ames, B. N. (1991) Immunoaffinity Isolation of Urinary 8-Hydroxy-2'-deoxyguanosine and 8-Hydroxyguanine and Quantitation of 8-Hydroxy-2'-deoxyguanosine in DNA by Polyclonal Antibodies. Carcinogenesis 12, 865-871. check for PDF

278 Ames, B. N. and Gold, L. S. (1991) Carcinogenesis Mechanisms: The Debate Continues. (Letter) Science 252, 902. check for PDF

279 Ames, B. N. (1991) Natural Carcinogens and Dioxin. The Science of the Total Environment 104, 159-166. check for PDF

280 Ames, B. N. and Gold, L. S. (1991) Mitogenesis, Mutagenesis, and Animal Cancer Tests. In: Chemically Induced Cell Proliferation: Implications for Risk Assessment, B. Butterworth T. Slaga, W. Farland and M. McClain, eds. Prog. Clin. Biol. Res. 369, (Alan R. Liss, New York, NY), pp. 1-20. check for PDF

281 Tartaglia, L. A., Storz, G., Farr, S. B. and Ames, B. N. (1991) The Bacterial Adaptation to Hydrogen Peroxide Stress. In: Oxidative Stress: Oxidants and Antioxidants, H. Sies, ed., (Academic Press, London, England), pp. 155-169. check for PDF

282 Frei, B., Forte, T. M., Ames, B. N. and Cross, C. E. (1991) Gas Phase Oxidants of Cigarette Smoke Induce Lipid Peroxidation and Changes in Lipoprotein Properties in Human Blood Plasma: Protective Effects of Ascorbic Acid. Biochem. J. 277, 133-138. check for PDF

283 Ames, B. N. (1991) Oxygen Radicals and 8-Hydroxyguanine in DNA. Jpn. J. Cancer Res. 82, inside cover. check for PDF

284 Ames, B. N. (1991) Foreward: Diet and the Prevention of Disease. In: Micronutrients in Health and in Disease Prevention, A. Bendich and C. E. Butterworth Jr., eds., (Marcel Dekker, Inc., New York, NY), pp. v - vii. check for PDF

285 Ames, B. N. and Gold, L. S. (1991) Natural Chemicals, Synthetic Chemicals, Risk Assessment, and Cancer. In: Xenobiotics and Cancer: Implications of Chemical Carcinogenesis and Cancer Chemotherapy, L. Ernster et al. eds. Proceedings of International Symposium of the Princess Takamatsu Cancer Research Fund, Japan Sci. Soc. Press, Tokyo (Taylor and Francis, London, England), pp. 303-314. check for PDF

286 Ames, B. N. and Gold, L. S. (1991) Endogenous Mutagens and the Causes of Aging and Cancer. Mutat. Res. 250, 3-16. check for PDF

287 Fraga, C. G., Motchnik, P. A., Shigenaga, M. K., Helbock, H. J., Jacob, R. and Ames, B. N. (1991) Ascorbic Acid Protects Against Endogenous Oxidative DNA Damage in Human Sperm. Proc. Natl. Acad. Sci. USA 88, 11003-11006. check for PDF

287a Stocker, R. and Frei, B. (1991) Endogenous Antioxidant Defenses in Human Blood Plasma. In: Oxidative Stress: Oxidants and Antioxidants, H. Sies, ed. (Academic Press, Orlando, FL), 213-243. check for PDF

288 Jacob, R. A., Kelley, D. S., Pianalto, F. S., Swendseid, M. E., Henning, S. M., Zhang, J. Z., Ames, B. N., Fraga, C. G. and Peters, J. H. (1991) Immunocompetence and Oxidant Defense During Ascorbate Depletion of Healthy Men. Am. J. Clin. Nutr. 54, 1302S-1309S. check for PDF

289 Ames, B. N. and Gold, L. S. (1991) Mitogenesis, Mutagenesis, and Rodent Cancer Tests. In: Origins of Human Cancer. J Brugge, T. Curran, E. Harlow, F. McCormick, eds. CSHL Symposium on the Origins of Human Cancer, (Cold Spring Harbor Press, Cold Spring Harbor, NY), pp. 125-135. check for PDF

290 Gold, L. S., Slone, T. H., Manley, N. B., Garfinkel, G. F., Hudes, E. S., Rohrbach, L. and Ames, B. N. (1991) The Carcinogenic Potency Database: Analyses of 4000 Chronic Animal Cancer Experiments Published in the General Literature and by the U. S. National Cancer Institute/ National Toxicology Program. Conference on Data Bases of Genotoxicity and Carcinogenicity and their Usefulness for Hazard Evaluations, held in Genova, Italy, January 1991. Environ. Health Perspect. 96, 11-15. check for PDF

291 Ames, B. N. and Gold, L. S. (1991) Misconceptions on Pollution and the Causes of Cancer. L'actualit? chimique, pp. 391-402. [Reprint of #265] check for PDF

292 Ames, B. N., Shigenaga, M. K. and Park. E.-M. (1991) DNA Damage by Endogenous Oxidants as a Cause of Aging and Cancer. In: Oxidative Damage and Repair: Clinical, Biological, and Medical Aspects., Kelvin J.A. Davies, ed. (Proceedings of the International Society for Free Radical Research, November 14-20, 1990), (Pergamon Press Inc., New York, NY), pp. 181-187. check for PDF

292a Reznick, A. Z., Cross, C. E., Hu, M.-L., Suzuki, Y. J., Khwaja, S., Safadi, A., Motchnik, P. A., Packer, L. and Halliwell, B. (1991) Modification of Plasma Proteins by Cigarette Smoke as Measured by Protein Carbonyl Formation. Biochem. J. 286, 607-611. check for PDF

292b Ames. B. N. (1991) Diet and the Causes of Cancer and Aging. In: The Future of Mankind and Earth, (Proceedings of the NODAI International Symposium 1991), pp. 165-187. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
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