Bruce N. Ames 2001 Publications

438. Gold, L.S., Slone, T.H., and Ames, B.N. (2001) Natural and Synthetic Chemicals in the Diet: A Critical Analysis of Possible Cancer Hazards. In: Issues in Environmental Science and Technology: Food Safety and Food Quality, R.E. Hester & R.M. Harrison, eds. (Royal Society of Chemistry, Cambridge, UK), No. 15, pp. 95-128. check for PDF

439. Ames, B.N. (2001) DNA Damage From Micronutrient Deficiencies is Likely to be a Major Cause of Cancer. Mutat. Res. 475, 7-20. check for PDF

440. Gold, L.S., Slone, T. H., Ames, B. N., and Manley, N. B. (2001) Pesticide Residues in Food and Cancer Risk: A Critical Analysis. In: Handbook of Pesticide Toxicology, R. Krieger, ed. (Academic Press, San Diego, CA) 2nd ed., pp. 799-843. check for PDF

441. Crott, J.W., Mashiyama, S.T., Ames, B.N., and Fenech, M. (2001) The Effect of Folic Acid Deficiency and MTHFR C677T Polymorphism on Chromosome Damage in Human Lymphocytes in Vitro. Cancer Epidemiol. Biomarkers Prev. 10, 1089-1096. check for PDF

442. Mayr, C. A., Woodall, A. A. and Ames, B. N. (2001) DNA Damage to Sperm from Micronutrient Deficiency May Increase the Risk of Birth Defects and Cancer in Offspring. In: Preventive Nutrition: The Comprehensive Guide for Health Professionals, A. Bendich and R. J. Deckelbaum, eds. (Humana Press, Inc., Totowa NJ), p. 373-386. check for PDF

443. Crott, J.W., Mashiyama, S.T., Ames, B.N., and Fenech, M.F. (2001) Methylenetetrahydrofolate Reductase C677t Polymorphism Does Not Alter Folic Acid Deficiency-Induced Uracil Incorporation into Primary Human Lymphocyte DNA In Vitro. Carcinogenesis 22, 1019-1025. check for PDF

444. Wallock, L.M., Tamura, T., Mayr, C.A., Johnston, K.E., Ames, B.N., and Jacob, R.A. (2001) Low Seminal Plasma Folate Concentrations are Associated with Low Sperm Density and Count in Male Smokers and Nonsmokers. Fertil. & Steril. 75, 252-259. check for PDF

445. Atamna, H., Robinson, C., Ingersoll, R., and Ames, B.N. (2001) N-t-Butyl Hydroxylamine is an Antioxidant that Reverses Age-related Changes in Mitochondria In Vivo and In Vitro. FASEB J. 15, 2196-2204. check for PDF

446. Jiang, Q., Christen, S., Shigenaga, M.K., and Ames, B.N. (2001) γ-Tocopherol, the Major Form of Vitamin E in the US Diet, Deserves More Attention. Am. J. Clin. Nutr.. 74, 714-722. check for PDF

447. Atamna, H., Liu, J. and B. N. Ames (2001) Heme Deficiency Selectively Interrupts Assembly of Mitochondrial Complex IV in Human Fibroblasts: Relevance to Aging. J. Biol. Chem. 276, 48410-48416. check for PDF

448. Girault, I., Karu, A.E., Schaper, M., Barcellos-Hoff, M.H., Hagen, T., Vogel, D.S., Ames, B.N., Christen, S., and Shigenaga, M.K. (2001) Immunodetection of 3-nitrotyrosine in the Liver of Zymosan-treated Rats with a New Monoclonal Antibody: Comparison to Analysis by HPLC. Free Radic. Biol. Med. 31, 1375-1387. check for PDF

448a. Liu, J., Wang, X., and Mori, A. (2001) Antioxidant Mechanism of the Anti-stress Effects of Medicinal Herbs: A Biochemical, Pharmacological, and Toxicological Study. In: Antioxidant Mechanism of Medicinal Herbs, A. Mori and T. Satoh, eds. (PJD Publications, Ltd., Westbury, NY), pp. 355-386.

449. Ames, B.N., Liu, J., and Atamna, H. (2001) Delaying Aging with Mitochondrial Micronutrients and Antioxidants. The Scientific World Journal 1, 81-82SR. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Dr. Ames current lecture abstract presented at CHORI, January 11, 2012 - Lecture Title: Vitamin and Mineral Inadequacy Accelerates Aging-Associated Diseases
Go to media page

Information on Juvenon

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