Bruce N. Ames 1978 Publications

100 Donahue, E. V., McCann, J. and Ames, B. N. (1978) Detection of Mutagenic Impurities in Carcinogens and Noncarcinogens by High-Pressure Liquid Chromatography and the Salmonella/Microsome Test. Cancer Res. 38, 431-438. get PDF

101 Alper, M. D. and Ames, B. N. (1978) Transport of Antibiotics and Metabolite Analogs by Systems Under Cyclic AMP Control: Positive Selection of Salmonella typhimurium cya and crp Mutants. J. Bacteriol. 133, 149-157. get PDF

102 Gold, M. D., Blum, A. and Ames, B. N. (1978) Another Flame Retardant, Tris-(1,3-Dichloro-2-Propyl) Phosphate, and Its Expected Metabolites Are Mutagens. Science 200, 785-787. get PDF

102a Lofroth, G. (1978) The Mutagenicity of Hexavalent Chromium is Decreased by Microsomal Metabolism. Naturwissenschaften 65, S.207.

102b Lofroth, G. (1978) The Mutagenicity of Dichloroacetaldehyde. Z. Naturforsch 33c, 783-785.

103 Ames, B. N. (1978) Environmental Chemicals Causing Cancer and Genetic Birth Defects: Developing a Strategy to Minimize Human Exposure (California Policy Seminar Series, Monograph #2, Institute of Governmental Studies, University of California, Berkeley). get PDF

104 Blum, A., Gold, M. D., Ames, B. N., Kenyon, C., Jones, F. R., Hett, E. A., Dougherty, R. C., Horning, E. C., Dzidic, I., Carroll, D. I., Stillwell, R. N. and Thenot, J.-P. (1978) Children Absorb Tris-BP Flame Retardant from Sleepwear: Urine Contains the Mutagenic Metabolite, 2,3-Dibromopropanol. Science 201, 1020-1023. get PDF

105 Ames, B. N. (1978) Environmental Chemicals Causing Cancer and Genetic Birth Defects. In: DNA Repair Mechanisms (ICN-UCLA Symposia on Molecular and Cellular Biology, Vol. IX), P. C. Hanawalt, E. C. Friedberg and C. F. Fox, eds. (Academic Press, New York, NY), pp. 691-698. get PDF

106 McCann, J. and Ames, B. N. (1978) The Salmonella/Microsome Mutagenicity Test: Predictive Value for Animal Carcinogenicity. In: Mutagenesis. Advances in Modern Toxicology, Vol. V, W. G. Flamm and M. A. Mehlman, eds. (Hemisphere, Washington, D.C.), pp. 87-108. get PDF

106a Walker, G. C. (1978) Isolation and Characterization of Mutants of the Plasmid pKM101 Deficient in Their Ability to Enhance Mutagenesis and Repair. J. Bacteriol. 133, 1203-1211.

106b Walker, G. C. (1978) Inducible Reactivation and Mutagenesis of UV-Irradiated Bacteriophage P22 in Salmonella typhimurium LT2 Containing the Plasmid pKM101. J. Bacteriol. 135, 415-421.

107 Ames, B. N. (1978) In Vitro Testing of Carcinogens and Mutagens. In: Structural Correlates of Carcinogenesis and Mutagenesis, I. M. Asher and C. Zervos, eds. (Proceedings of the Second FDA Office of Science Summer Symposium, U.S. Naval Academy, 1977), pp. 27-33. get PDF

108 Ames, B. N. (1978) Environmental Chemicals Causing Cancer and Genetic Birth Defects: Mutagenicity Testing for Reactive Metabolites. In: Advances in Pharmacology and Therapeutics: Toxicology, Vol. 9 (Proceedings of the 7th International Conference of Pharmacology, Paris), Y. Cohen, ed. (Pergamon Press, Oxford, England), pp. 29-40. get PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
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