Bruce N. Ames 2006 Publications

507. Ames, B.N., Suh, J. and Liu, J. (2006) Enzymes Lose Binding Affinity (increase Km) for Coenzymes and Substrates with Age: A Strategy for Remediation. In: Nutritional Genomics: Discovering the Path to Personalized Nutrition. Kaput, J. and Rodriguez, RL. (Eds). John Wiley and Sons, Inc., Hoboken, NJ. 277-291. check for PDF

508. McCann, J., Hudes, M., Ames, B.N. (2006). An Overview of Evidence for a Causal Relationship Between Dietary Availability of Choline During Development and Cognitive Function in Offspring. Neuroscience and Biobehavioral Reviews, 30: 696-712. check for PDF

509. McCann, J., and Ames, BN. (2006) Letter to the Editor (Response to P. Wainwright): Scientific Precision and Deciding Whether to Supplement Infant Formulas With LCPUFAs, Am J Clin Nutr., 83: 920-1. check for PDF

510. Ames, B (2006) Low micronutrient intake may accelerate the degenerative diseases of aging through allocation of scarce micronutrients by triage. Proc. Natl. Acad. Sciences, U.S.A., 103:17589-94. check for PDF

510a. Atamna, H and Boyle, K. (2006) Amyloid-β peptide binds with heme to form a peroxidase: Relationship to the cytopathologies of Alzheimer's disease. PNAS 103: 3381-6. check for PDF

510b. Atamna, H. (2005) Heme Binding to Amyloid-β Peptide: Mechanistic role in Alzheimer's Disease. J Alzheimer's Dis, 10:255-66. check for PDF

510c. Cui X, Suo P, Zhang Q, Li X, Hu Y, Long J, Packer L, Liu J (2006) Chronic Systemic D-Galactose Exposure Induces Memory Loss, Neurodegeneration, and Oxidative Damage in Mice: Protective Effects of R-α-Lipoic Acid. J Neuro Res. 83:1584-90. check for PDF

510d. Luo C, Wang XM, Long JG and Liu J. (2006) An NADH-Tetrazolium-Coupled Sensitive Assay for Malate Dehydrogenase in Mitochondria and Crude Tissue Homogenates. J. Biochem. Biophys. Meth. 68:101-111. check for PDF

510e. Long JG, Wang XM, Gao HX, Liu Z, Liu CS, Miao MY, and Liu J. (2006) Malonaldehyde acts as a mitochondrial toxin: Inhibitory effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Life Sciences. 79:1466-1472. check for PDF

510f. Sun LJ, Luo C, Long JG, Wei DZ, and Liu, J. (2006) Acrolein is a mitochondrial toxin: Effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Mitochondrion 6:136-142. check for PDF

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Contact Information

Mailing Address:
Children's Hospital Oakland Research Institute (CHORI),
5700 Martin Luther King Jr. Way, Oakland CA 94609.
Phone: (510) 450-7625
CHORI E-mail: bames@chori.org

Recent News

November 2008

October 2008

  • A new web graphic of Gold, Ames & Slone uses a Margin of Exposure index to provide a broad perspective on possible cancer hazards from human exposures to chemicals that cause cancer in high dose rodent tests. Exposures include high historical exposures to workers, pharmaceuticals, natural chemicals in the average diet (e.g., natural pesticides that plants produce to defend themselves), air pollutants, food additives, and pesticide residues. Human exposure levels range from close to the rodent carcinogenic dose for a few historical exposures in the workplace to a billion times less the rodent carcinogenic dose for some pesticide residues. Human consumption of the background of natural chemicals in food is usually closer to the rodent carcinogenic dose than pesticide residues or pollutants, and half the natural chemicals tested are carcinogenic in high dose tests. Recent risk assessment methods indicate that for some chemicals the mechanism of carcinogenesis in rodents at high dose is not relevant to humans.

June 2008

  • The CHORI webpage news article on Killilea & Ames magnesium Study:
    read article
  • Ames & Killilea News Study listed in 'AFAR Grantee's In the News' list
    go to AFAR site

April 2008

October 2007

For information on symposium proceedings and media please go to the Second Annual International Bruce Ames Symposium Website held at UC Davis.

Downloadable Media

The downloadable media section is constantly being updated. You will find that some links are not yet available. We apologize for the inconvenience and request that you come back periodically, to check for future availability.

Among the items available for download is a high resolution TIFF formated photograph of Dr. Ames (300 dpi resolution, and a 7MB ZIP archive), and Dr. Ames' streamed video lectures.

Dr. Ames' publications are also available by request to students and colleagues.
To request copies of Dr. Ames' publications, please fill out this electronic form.
Go to media page

Information on Juvenon

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